Details
Manufacturer supply 5-Fluorosalicylic acid 345-16-4 with sufficient stock and high standard
- Molecular Formula: C7H5FO3
- Molecular Weight: 156.113
- Appearance/Colour: light yellow powder
- Vapor Pressure: 0.0624mmHg at 25°C
- Melting Point: 177-179 °C(lit.)
- Refractive Index: 1.554
- Boiling Point: 307.4 °C at 760 mmHg
- PKA: 2.68±0.10(Predicted)
- Flash Point: 139.7 °C
- PSA： 57.53000
- Density: 1.492 g/cm3
- LogP: 1.22950
5-Fluorosalicylic acid(Cas 345-16-4) Usage
|
Synthesis Reference(s) |
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8 |
InChI:InChI=1/C6H3ClFNO2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H
345-16-4 Relevant articles
A versatile approach for the synthesis of para -substituted arenes via palladium-catalyzed C-H functionalization and protodecarboxylation of benzoic acids
Pan, Shulei,Zhou, Bo,Zhang, Yanghui,Shao, Changdong,Shi, Guangfa
supporting information, p. 277 - 281 (2016/01/20)
While a great number of ortho C-H functi...
The reaction of hydroxylamine with aspirin
Medeiros, Michelle,Souza, Bruno S.,Orth, Elisa S.,Brandao, Tiago A. S.,Rocha, Willian,Kirby, Anthony J.,Nome, Faruk
scheme or table, p. 461 - 476 (2011/10/05)
Hydroxylamine reacts with aspirin in aqu...
A kinetic study into the hydrolysis of the ochratoxins and analogues by carboxypeptidase A
Stander,Steyn,Van der Westhuizen,Payne
, p. 302 - 304 (2007/10/03)
The hydrolyses of the ochratoxins and an...
Fluorophenols and (trifluoromethyl)phenols as substrates of site-selective metalation reactions: To protect or not to protect
Marzi, Elena,Mongin, Florence,Spitaleri, Andrea,Schlosser, Manfred
, p. 2911 - 2915 (2007/10/03)
O-Methoxymethyl (MOM) protected fluoroph...
345-16-4 Process route
-
-
N-(5-fluoro-2-hydroxybenzoyl)phenylalanine
-
-
63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine
-
-
345-16-4
5-fluoro-2-hydroxybenzoic acid
| Conditions | Yield |
|---|---|
|
With
tris hydrochloride; sodium chloride; carboxypeptidase A;
In
water;
for 0.0833333h;
pH=8.0;
Enzyme kinetics;
|
-
-
455-38-9
3-fluorobenzoic acid
-
-
345-16-4
5-fluoro-2-hydroxybenzoic acid
| Conditions | Yield |
|---|---|
|
With
oxygen; potassium acetate; palladium diacetate; p-benzoquinone;
In
N,N-dimethyl acetamide;
at 115 ℃;
for 15h;
regioselective reaction;
Schlenk technique;
|
345-16-4 Upstream products
-
445-93-2
2-ethoxy-5-fluoro-benzoic acid
-
394-04-7
5-fluoro-2-methoxybenzoic acid
-
89-57-6
5-Aminosalicylic Acid
-
394-32-1
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one
345-16-4 Downstream products
-
443-12-9
ethyl 5-fluoro-2-hydroxybenzoate
-
448-40-8
2-acetoxy-5-fluoro benzoic acid
-
391-92-4
methyl 5-fluoro-2-hydroxybenzoate
-
77068-06-5
4'-iodo-5-fluoro-2'-methylsalicylanilide
Related Products
-
O-NITROPHENYL N-BUTYRATECAS：2487-26-5
-
Acid Violet 17CAS：4129-84-4
-
